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A Whole Cell Assay to Measure Caspase-6 Activity by Detecting Cleavage of Lamin A/C
Caspase-6 is a cysteinyl protease implicated in neurodegenerative conditions including Alzheimer's and Huntington's disease making it an attractive target for therapeutic intervention. A greater understanding of the role of caspase-6 in disease has been hampered by a lack of suitable cellu...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257251/ https://ncbi.nlm.nih.gov/pubmed/22253931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030376 |
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