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Adeno-Associated Virus 2 Infection Requires Endocytosis through the CLIC/GEEC Pathway
Adeno-associated viruses (AAVs) are non-pathogenic, non-enveloped, single-stranded DNA viruses in development as gene therapy vectors. AAV internalization was postulated to proceed via a dynamin-dependent endocytic mechanism. Revisiting this, we find that infectious endocytosis of the prototypical A...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257174/ https://ncbi.nlm.nih.gov/pubmed/22177561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.10.014 |
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