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The CXCR7 chemokine receptor promotes B-cell retention in the splenic marginal zone and serves as a sink for CXCL12
The splenic marginal zone (MZ) is comprised of specialized populations of B cells, dendritic cells, and macrophages that are uniquely arrayed outside the white pulp follicles to screen the blood for bacterial and other particulate Ags. Mechanisms responsible for MZ B-cell formation, localization, re...
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Autores principales: | , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
American Society of Hematology
2012
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257011/ https://ncbi.nlm.nih.gov/pubmed/22110250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-343608 |
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