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The CXCR7 chemokine receptor promotes B-cell retention in the splenic marginal zone and serves as a sink for CXCL12

The splenic marginal zone (MZ) is comprised of specialized populations of B cells, dendritic cells, and macrophages that are uniquely arrayed outside the white pulp follicles to screen the blood for bacterial and other particulate Ags. Mechanisms responsible for MZ B-cell formation, localization, re...

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Autores principales: Wang, Hongsheng, Beaty, Natalie, Chen, Sophia, Qi, Chen-Feng, Masiuk, Marek, Shin, Dong-Mi, Morse, Herbert C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257011/
https://ncbi.nlm.nih.gov/pubmed/22110250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-343608
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