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HTLV-1 bZIP factor impairs cell-mediated immunity by suppressing production of Th1 cytokines

Adult T-cell leukemia (ATL) patients and human T-cell leukemia virus-1 (HTLV-1) infected individuals succumb to opportunistic infections. Cell mediated immunity is impaired, yet the mechanism of this impairment has remained elusive. The HTLV-1 basic leucine zipper factor (HBZ) gene is encoded in the...

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Bibliografiske detaljer
Main Authors: Sugata, Kenji, Satou, Yorifumi, Yasunaga, Jun-ichirou, Hara, Hideki, Ohshima, Kouichi, Utsunomiya, Atae, Mitsuyama, Masao, Matsuoka, Masao
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257009/
https://ncbi.nlm.nih.gov/pubmed/22123848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-357459
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