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Activity of alemtuzumab monotherapy in treatment-naive, relapsed, and refractory severe acquired aplastic anemia

Antithymocyte globulin (ATG) + cyclosporine is effective in restoring hematopoiesis in severe aplastic anemia (SAA). We hypothesized that the humanized anti-CD52 mAb alemtuzumab might be active in SAA because of its lymphocytotoxic properties. We investigated alemtuzumab monotherapy from 2003-2010 i...

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Bibliografiske detaljer
Main Authors: Scheinberg, Phillip, Nunez, Olga, Weinstein, Barbara, Scheinberg, Priscila, Wu, Colin O., Young, Neal S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257005/
https://ncbi.nlm.nih.gov/pubmed/22067384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-352328
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