Immunization of Mice With Vibrio cholerae Outer-Membrane Vesicles Protects Against Hyperinfectious Challenge and Blocks Transmission

Background. Vibrio cholerae excreted by cholera patients is “hyperinfectious” (HI), which can be modeled by passage through infant mice. Immunization of adult female mice with V. cholerae outer-membrane vesicles (OMVs) passively protects suckling mice from challenge. Although V. cholerae is unable t...

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Hauptverfasser: Bishop, Anne L., Tarique, Abdullah A., Patimalla, Bharathi, Calderwood, Stephen B., Qadri, Firdausi, Camilli, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256948/
https://ncbi.nlm.nih.gov/pubmed/22147790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir756
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