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BMP2 Protein Regulates Osteocalcin Expression via Runx2-mediated Atf6 Gene Transcription

Bone morphogenetic protein 2 (BMP2) activates unfolded protein response (UPR) transducers, such as PERK and OASIS, in osteoblast cells. ATF6, a bZIP transcription factor, is also a UPR transducer. However, the involvement of ATF6 in BMP2-induced osteoblast differentiation has not yet been elucidated...

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Bibliografiske detaljer
Main Authors: Jang, Won-Gu, Kim, Eun-Jung, Kim, Don-Kyu, Ryoo, Hyun-Mo, Lee, Keun-Bae, Kim, Sun-Hun, Choi, Hueng-Sik, Koh, Jeong-Tae
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256879/
https://ncbi.nlm.nih.gov/pubmed/22102412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253187
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