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β-Glucan from Lentinus edodes Inhibits Nitric Oxide and Tumor Necrosis Factor-α Production and Phosphorylation of Mitogen-activated Protein Kinases in Lipopolysaccharide-stimulated Murine RAW 264.7 Macrophages

Lentinan (LNT), a β-glucan from the fruiting bodies of Lentinus edodes, is well known to have immunomodulatory activity. NO and TNF-α are associated with many inflammatory diseases. In this study, we investigated the effects of LNT extracted by sonication (LNT-S) on the NO and TNF-α production in LP...

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Detalhes bibliográficos
Main Authors: Xu, Xiaojuan, Yasuda, Michiko, Nakamura-Tsuruta, Sachiko, Mizuno, Masashi, Ashida, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256862/
https://ncbi.nlm.nih.gov/pubmed/22102286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.297887
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