Roles of Endonuclease V, Uracil-DNA Glycosylase, and Mismatch Repair in Bacillus subtilis DNA Base-Deamination-Induced Mutagenesis

The disruption of ung, the unique uracil-DNA-glycosylase-encoding gene in Bacillus subtilis, slightly increased the spontaneous mutation frequency to rifampin resistance (Rif(r)), suggesting that additional repair pathways counteract the mutagenic effects of uracil in this microorganism. An alternat...

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Bibliographic Details
Main Authors: López-Olmos, Karina, Hernández, Martha P., Contreras-Garduño, Jorge A., Robleto, Eduardo A., Setlow, Peter, Yasbin, Ronald E., Pedraza-Reyes, Mario
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256648/
https://ncbi.nlm.nih.gov/pubmed/22056936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06082-11
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