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Evidence that the Folate-Dependent Proteins YgfZ and MnmEG Have Opposing Effects on Growth and on Activity of the Iron-Sulfur Enzyme MiaB

The folate-dependent protein YgfZ of Escherichia coli participates in the synthesis and repair of iron-sulfur (Fe-S) clusters; it belongs to a family of enzymes that use folate to capture formaldehyde units. Ablation of ygfZ is known to reduce growth, to increase sensitivity to oxidative stress, and...

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Autors principals: Waller, Jeffrey C., Ellens, Kenneth W., Hasnain, Ghulam, Alvarez, Sophie, Rocca, James R., Hanson, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256646/
https://ncbi.nlm.nih.gov/pubmed/22081392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.06226-11
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