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Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories

Rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR) kinase, has attracted interest as a possible prophylactic for post-traumatic stress disorder (PTSD)-associated fear memories. We report here that although rapamycin (40 mg/kg, i.p.) disrupted the consolidation and reconsolidation of...

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Hlavní autoři: Glover, Ebony M., Ressler, Kerry J., Davis, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256567/
https://ncbi.nlm.nih.gov/pubmed/21036892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.1908310
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