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Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories

Rapamycin, an inhibitor of the mammalian target of rapamycin (mTOR) kinase, has attracted interest as a possible prophylactic for post-traumatic stress disorder (PTSD)-associated fear memories. We report here that although rapamycin (40 mg/kg, i.p.) disrupted the consolidation and reconsolidation of...

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Detalhes bibliográficos
Main Authors: Glover, Ebony M., Ressler, Kerry J., Davis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256567/
https://ncbi.nlm.nih.gov/pubmed/21036892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.1908310
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