Fibrinogen-induced increased pial venular permeability in mice

Elevated blood level of Fibrinogen (Fg) is commonly associated with vascular dysfunction. We tested the hypothesis that at pathologically high levels, Fg increases cerebrovascular permeability by activating matrix metalloproteinases (MMPs). Fibrinogen (4 mg/mL blood concentration) or equal volume of...

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Detalhes bibliográficos
Main Authors: Muradashvili, Nino, Qipshidze, Natia, Munjal, Charu, Givvimani, Srikanth, Benton, Richard L, Roberts, Andrew M, Tyagi, Suresh C, Lominadze, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256415/
https://ncbi.nlm.nih.gov/pubmed/21989482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.144
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