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2′-O-methylation of the wobble residue of elongator pre-tRNA(Met) in Haloferax volcanii is guided by a box C/D RNA containing unique features
The wobble residue C34 of Haloferax volcanii elongator tRNA(Met) is 2′-O-methylated. Neither a protein enzyme nor a guide RNA for this modification has been described. In this study, we show that this methylation is guided by a box C/D RNA targeting the intron-containing precursor of the tRNA. This...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256356/ https://ncbi.nlm.nih.gov/pubmed/21654217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.5.16015 |
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