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Brh2 domain function distinguished by differential cellular responses to DNA damage and replication stress

Mutants of the fungus Ustilago maydis defective in the RecQ helicase Blm are highly sensitive to killing by the DNA replication stressor hydroxyurea. This sensitivity or toxicity is dependent on the homologous recombination (HR) system and apparently results from formation of dead-end HR DNA interme...

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Bibliografske podrobnosti
Main Authors: Kojic, Milorad, Holloman, William K.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256287/
https://ncbi.nlm.nih.gov/pubmed/22171788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07935.x
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