Polar Invasion and Translocation of Neisseria meningitidis and Streptococcus suis in a Novel Human Model of the Blood-Cerebrospinal Fluid Barrier

Acute bacterial meningitis is a life-threatening disease in humans. Discussed as entry sites for pathogens into the brain are the blood-brain and the blood-cerebrospinal fluid barrier (BCSFB). Although human brain microvascular endothelial cells (HBMEC) constitute a well established human in vitro m...

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Hauptverfasser: Schwerk, Christian, Papandreou, Thalia, Schuhmann, Daniel, Nickol, Laura, Borkowski, Julia, Steinmann, Ulrike, Quednau, Natascha, Stump, Carolin, Weiss, Christel, Berger, Jürgen, Wolburg, Hartwig, Claus, Heike, Vogel, Ulrich, Ishikawa, Hiroshi, Tenenbaum, Tobias, Schroten, Horst
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256222/
https://ncbi.nlm.nih.gov/pubmed/22253884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030069
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