Insulin-Like Growth Factor-1 Promotes G(1)/S Cell Cycle Progression through Bidirectional Regulation of Cyclins and Cyclin-Dependent Kinase Inhibitors via the Phosphatidylinositol 3-Kinase/Akt Pathway in Developing Rat Cerebral Cortex

Although survival-promoting effects of insulin-like growth factor-1 (IGF-1) during neurogenesis are well characterized, mitogenic effects remain less well substantiated. Here, we characterize cell cycle regulators and signaling pathways underlying IGF-1 effects on embryonic cortical precursor prolif...

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Main Authors: Mairet-Coello, Georges, Tury, Anna, DiCicco-Bloom, Emanuel
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2009
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256126/
https://ncbi.nlm.nih.gov/pubmed/19158303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1700-08.2009
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