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Pharmacokinetics of Doxycycline in Adults with Cystic Fibrosis

Cystic fibrosis (CF) is characterized by a chronic neutrophilic inflammatory response resulting in airway remodeling and progressive loss of lung function. Doxycycline is a tetracycline antibiotic that inhibits matrix metalloproteinase 9, a protease known to be associated with the severity of lung d...

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Autori principali: Beringer, Paul M., Owens, Heather, Nguyen, Albert, Benitez, Debbie, Rao, Adupa, D'Argenio, David Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256044/
https://ncbi.nlm.nih.gov/pubmed/22024822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05710-11
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