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Genetic Environment and Stability of cfr in Methicillin-Resistant Staphylococcus aureus CM05

The Cfr methyltransferase confers resistance to many 50S ribosomal subunit-targeted antibiotics, including linezolid (LZD), via methylation of the 23S rRNA base A2503 in the peptidyl transferase center. Methicillin-resistant Staphylococcus aureus strain CM05 is the first clinical isolate documented...

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Detalhes bibliográficos
Main Authors: Locke, Jeffrey B., Rahawi, Shahad, LaMarre, Jacqueline, Mankin, Alexander S., Shaw, Karen Joy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256036/
https://ncbi.nlm.nih.gov/pubmed/22024827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05420-11
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