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The Oligo-Acyl Lysyl Antimicrobial Peptide C(12)K-2β(12) Exhibits a Dual Mechanism of Action and Demonstrates Strong In Vivo Efficacy against Helicobacter pylori

Helicobacter pylori has developed antimicrobial resistance to virtually all current antibiotics. Thus, there is a pressing need to develop new anti-H. pylori therapies. We recently described a novel oligo-acyl-lysyl (OAK) antimicrobial peptidomimetic, C(12)K-2β(12), that shows potent in vitro bacter...

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Detaylı Bibliyografya
Asıl Yazarlar: Makobongo, Morris O., Gancz, Hanan, Carpenter, Beth M., McDaniel, Dennis P., Merrell, D. Scott
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256018/
https://ncbi.nlm.nih.gov/pubmed/22064541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00689-11
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