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Ultrashort Peptide Bioconjugates Are Exclusively Antifungal Agents and Synergize with Cyclodextrin and Amphotericin B

Many natural broad-spectrum cationic antimicrobial peptides (AMPs) possess a general mode of action that is dependent on lipophilicity and charge. Modulating the lipophilicity of AMPs by the addition of a fatty acid has been an effective strategy to increase the lytic activity and can further broade...

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Autores principales: Arnusch, Christopher J., Ulm, Hannah, Josten, Michaele, Shadkchan, Yana, Osherov, Nir, Sahl, Hans-Georg, Shai, Yechiel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256016/
https://ncbi.nlm.nih.gov/pubmed/22006001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00468-11
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