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α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction
We have developed an in vitro assay to study actin assembly at cadherin-enriched cell junctions. Using this assay, we demonstrate that cadherin-enriched junctions can polymerize new actin filaments but cannot capture preexisting filaments, suggesting a mechanism involving de novo synthesis. In agree...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255975/ https://ncbi.nlm.nih.gov/pubmed/22232703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103116 |
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