A Flucytosine-Responsive Mbp1/Swi4-Like Protein, Mbs1, Plays Pleiotropic Roles in Antifungal Drug Resistance, Stress Response, and Virulence of Cryptococcus neoformans

Cryptococcosis, caused by the basidiomycetous fungus Cryptococcus neoformans, is responsible for more than 600,000 deaths annually in AIDS patients. Flucytosine is one of the most commonly used antifungal drugs for its treatment, but its resistance and regulatory mechanisms have never been investiga...

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Autors principals: Song, Min-Hee, Lee, Jang-Won, Kim, Min Su, Yoon, Ja-Kyung, White, Theodore C., Floyd, Anna, Heitman, Joseph, Strain, Anna K., Nielsen, Judith N., Nielsen, Kirsten, Bahn, Yong-Sun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255937/
https://ncbi.nlm.nih.gov/pubmed/22080454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.05236-11
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