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Modification of the Untranslated Regions of Human Enterovirus 71 Impairs Growth in a Cell-Specific Manner

Human enterovirus 71 (HEV71) is the causative agent of hand, foot, and mouth disease and associated acute neurological disease. At present, little is known about the genetic determinants of HEV71 neurovirulence. Studies of related enteroviruses have indicated that the untranslated regions (UTRs), wh...

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Autors principals: Kok, Chee Choy, Phuektes, Patchara, Bek, Emily, McMinn, Peter C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255918/
https://ncbi.nlm.nih.gov/pubmed/22031931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00069-11
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