Potent Intratype Neutralizing Activity Distinguishes Human Immunodeficiency Virus Type 2 (HIV-2) from HIV-1

HIV-2 has a lower pathogenicity and transmission rate than HIV-1. Neutralizing antibodies could be contributing to these observations. Here we explored side by side the potency and breadth of intratype and intertype neutralizing activity (NAc) in plasma of 20 HIV-1-, 20 HIV-2-, and 11 dually HIV-1/2...

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Bibliografische gegevens
Hoofdauteurs: Özkaya Şahin, Gülşen, Holmgren, Birgitta, da Silva, Zacarias, Nielsen, Jens, Nowroozalizadeh, Salma, Esbjörnsson, Joakim, Månsson, Fredrik, Andersson, Sören, Norrgren, Hans, Aaby, Peter, Jansson, Marianne, Fenyö, Eva Maria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255861/
https://ncbi.nlm.nih.gov/pubmed/22072782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06315-11
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