Human Pulmonary Microvascular Endothelial Cells Support Productive Replication of Highly Pathogenic Avian Influenza Viruses: Possible Involvement in the Pathogenesis of Human H5N1 Virus Infection

Highly pathogenic avian influenza (HPAI) H5N1 viruses continue to cause sporadic human infections with a high fatality rate. Respiratory failure due to acute respiratory distress syndrome (ARDS) is a complication among hospitalized patients. Since progressive pulmonary endothelial damage is the hall...

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Main Authors: Zeng, Hui, Pappas, Claudia, Belser, Jessica A., Houser, Katherine V., Zhong, Weiming, Wadford, Debra A., Stevens, Troy, Balczon, Ron, Katz, Jacqueline M., Tumpey, Terrence M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255832/
https://ncbi.nlm.nih.gov/pubmed/22072765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06348-11
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