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Conserved Glycine 33 Residue in Flexible Domain I of Hepatitis C Virus Core Protein Is Critical for Virus Infectivity

Hepatitis C virus core protein forms the viral nucleocapsid and plays a critical role in the formation of infectious particles. In this study, we demonstrate that the highly conserved residue G33, located within domain 1 of the core protein, is important for the production of cell culture-infectious...

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Detalhes bibliográficos
Main Authors: Angus, Allan G. N., Loquet, Antoine, Stack, Séamus J., Dalrymple, David, Gatherer, Derek, Penin, François, Patel, Arvind H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255827/
https://ncbi.nlm.nih.gov/pubmed/22072760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05452-11
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