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Development of a Simvastatin Selection Marker for a Hyperthermophilic Acidophile, Sulfolobus islandicus

We report here a novel selectable marker for the hyperthermophilic crenarchaeon Sulfolobus islandicus. The marker cassette is composed of the sac7d promoter and the hmg gene coding for the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (P(sac7d)-hmg), which confers simvastatin resistance...

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Bibliografiske detaljer
Main Authors: Zheng, Tao, Huang, Qihong, Zhang, Changyi, Ni, Jinfeng, She, Qunxin, Shen, Yulong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255719/
https://ncbi.nlm.nih.gov/pubmed/22081574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.06095-11
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