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Development of a Simvastatin Selection Marker for a Hyperthermophilic Acidophile, Sulfolobus islandicus
We report here a novel selectable marker for the hyperthermophilic crenarchaeon Sulfolobus islandicus. The marker cassette is composed of the sac7d promoter and the hmg gene coding for the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (P(sac7d)-hmg), which confers simvastatin resistance...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255719/ https://ncbi.nlm.nih.gov/pubmed/22081574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.06095-11 |
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