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Orphan Nuclear Receptor PNR/NR2E3 Stimulates p53 Functions by Enhancing p53 Acetylation

Since inactivation of tumor suppressor p53 functions is one of the most common features of human cancer cells, restoring p53 expression and activity is an important focus in cancer therapy. Here we report identification of photoreceptor-specific nuclear receptor (PNR)/NR2E3 as a positive regulator o...

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Bibliografski detalji
Glavni autori: Wen, Zhi, Pyeon, Dohun, Wang, Yidan, Lambert, Paul, Xu, Wei, Ahlquist, Paul
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255696/
https://ncbi.nlm.nih.gov/pubmed/22025681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05513-11
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