Profound Alterations of Intestinal Microbiota following a Single Dose of Clindamycin Results in Sustained Susceptibility to Clostridium difficile-Induced Colitis

Antibiotic-induced changes in the intestinal microbiota predispose mammalian hosts to infection with antibiotic-resistant pathogens. Clostridium difficile is a Gram-positive intestinal pathogen that causes colitis and diarrhea in patients following antibiotic treatment. Clindamycin predisposes patie...

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Bibliografiske detaljer
Main Authors: Buffie, Charlie G., Jarchum, Irene, Equinda, Michele, Lipuma, Lauren, Gobourne, Asia, Viale, Agnes, Ubeda, Carles, Xavier, Joao, Pamer, Eric G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255689/
https://ncbi.nlm.nih.gov/pubmed/22006564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05496-11
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