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Abrogation of Neuraminidase Reduces Biofilm Formation, Capsule Biosynthesis, and Virulence of Porphyromonas gingivalis

The oral bacterium Porphyromonas gingivalis is a key etiological agent of human periodontitis, a prevalent chronic disease that affects up to 80% of the adult population worldwide. P. gingivalis exhibits neuraminidase activity. However, the enzyme responsible for this activity, its biochemical featu...

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Hlavní autoři: Li, Chen, Kurniyati, Hu, Bo, Bian, Jiang, Sun, Jianlan, Zhang, Weiyan, Liu, Jun, Pan, Yaping, Li, Chunhao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255687/
https://ncbi.nlm.nih.gov/pubmed/22025518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05773-11
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