Interleukin-4 (IL-4) and IL-13 Suppress Excessive Neutrophil Infiltration and Hepatocyte Damage during Acute Murine Schistosomiasis Japonica

Due to the importance of neutrophils and proinflammatory cytokines in schistosomal liver damage, we analyzed the mechanisms underlying neutrophil and proinflammatory responses in murine schistosomiasis japonica. We found that granulomatous inflammation around parasite eggs in the liver was greater i...

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Main Authors: Seki, Takenori, Kumagai, Takashi, Kwansa-Bentum, Bethel, Furushima-Shimogawara, Rieko, Anyan, William K., Miyazawa, Yuuki, Iwakura, Yoichiro, Ohta, Nobuo
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2012
Ábhair:
Fungal and Parasitic Infections
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255664/
https://ncbi.nlm.nih.gov/pubmed/22038918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05581-11
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