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Evaluation of Residual Promoter Activity in γ-Retroviral Self-inactivating (SIN) Vectors
Therapeutic gene delivery mediated by retroviral vectors has the advantage of stable integration into the host genome. A major safety concern for gene delivery achieved by murine leukemia virus (MLV)-based retroviral vectors is the activation of adjacent cellular genes including oncogenes following...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3255602/ https://ncbi.nlm.nih.gov/pubmed/22008914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.204 |
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