Highly skewed T-cell receptor V-beta chain repertoire in the bone marrow is associated with response to immunosuppressive drug therapy in children with very severe aplastic anemia

One of the major obstacles of immunosuppressive therapy (IST) in children with severe aplastic anemia (SAA) comes from the often months-long unpredictability of bone-marrow (BM) recovery. In this prospective study in children with newly diagnosed very severe AA (n=10), who were enrolled in the thera...

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Bibliografische gegevens
Hoofdauteurs: Schuster, F R, Hubner, B, Führer, M, Eckermann, O, Gombert, M, Dornmair, K, Binder, V, Reuther, S, Krell, P, Keller, T, Borkhardt, A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2011
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255274/
https://ncbi.nlm.nih.gov/pubmed/22829127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2011.6
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