Osmolarity and Glucose Differentially Regulate Aldose Reductase Activity in Cultured Mouse Podocytes

Podocyte injury is associated with progression of many renal diseases, including diabetic nephropathy. In this study we examined whether aldose reductase (AR), the enzyme implicated in diabetic complications in different tissues, is modulated by high glucose and osmolarity in podocyte cells. AR mRNA...

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Detaylı Bibliyografya
Asıl Yazarlar: Lewko, Barbara, Latawiec, Elżbieta, Maryn, Anna, Barczyńska, Anna, Pikuła, Michał, Zieliński, Maciej, Rybczyńska, Apolonia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255165/
https://ncbi.nlm.nih.gov/pubmed/22253613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/278963
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