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Bactericidal Antibiotics temporarily increase inflammation and worsen acute kidney injury in experimental sepsis

OBJECTIVE: To explore the relationships between bactericidal antimicrobial treatment of sepsis, inflammatory response, severity of AKI, and outcomes. DESIGN: Controlled laboratory experiment. SETTING: University laboratory. INTERVENTIONS: Sepsis was induced by cecal ligation and puncture (CLP) in 52...

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Detalhes bibliográficos
Main Authors: Peng, Zhi-Yong, Wang, Hong-Zhi, Srisawat, Nattachai, Wen, Xiaoyan, Rimmelé, Thomas, Bishop, Jeffery, Singbartl, Kai, Murugan, Raghavan, Kellum, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254710/
https://ncbi.nlm.nih.gov/pubmed/21926582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31822f0d2e
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