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Cotranscriptional folding kinetics of ribonucleic acid secondary structures

We develop a systematic helix-based computational method to predict RNA folding kinetics during transcription. In our method, the transcription is modeled as stepwise process, where each step is the transcription of a nucleotide. For each step, the kinetics algorithm predicts the population kinetics...

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Autori principali: Zhao, Peinan, Zhang, Wenbing, Chen, Shi-Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Institute of Physics 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254582/
https://ncbi.nlm.nih.gov/pubmed/22225186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3671644
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