Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I

BACKGROUND: The nonstructural protein 1 (NSP1) of rotavirus has been reported to block interferon (IFN) signaling by mediating proteasome-dependent degradation of IFN-regulatory factors (IRFs) and (or) the β-transducin repeat containing protein (β-TrCP). However, in addition to these targets, NSP1 m...

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Detalhes bibliográficos
Main Authors: Qin, Lan, Ren, Lili, Zhou, Zhuo, Lei, Xiaobo, Chen, Lan, Xue, Qinghua, Liu, Xinlei, Wang, Jianwei, Hung, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254192/
https://ncbi.nlm.nih.gov/pubmed/22152002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-526
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