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(+)-Sorangicin A: evolution of a viable synthetic strategy

An effective, asymmetric total synthesis of the antibiotic (+)-sorangicin A (1) has been achieved. Central to this venture was the development of first and second generation syntheses of the signature dioxabicyclo[3.2.1]octane core, the first featuring chemo- and stereoselective epoxide ring opening...

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Detalhes bibliográficos
Main Authors: Smith, Amos B., Dong, Shuzhi, Fox, Richard J, Brenneman, Jehrod B., Vanecko, John A., Maegawa, Tomohiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254116/
https://ncbi.nlm.nih.gov/pubmed/22247573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2011.09.035
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