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Targeting Cardiovascular Disease with Novel SIRT1 Pathways

The sirtuin (the mammalian homolog of silent information regulation 2 of yeast S.cerevisiae) 1 (SIRT1), a NAD-dependent histone deacetylase, has emerged as a critical regulator in response to oxidative stress. Through antagonism of oxidative stress-induced cell injury and through the maintenance of...

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Autors principals: Chong, Zhao Zhong, Wang, Shaohui, Shang, Yan Chen, Maiese, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254055/
https://ncbi.nlm.nih.gov/pubmed/22185448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fca.11.76
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