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Airway cells from atopic asthmatics exposed to ozone display an enhanced innate immune gene profile

This study identifies transcriptional phenotypes of sputum samples from normal volunteers and atopic asthmatics exposed to ozone. Network analyses suggest that asthmatics elevate immune signaling following oxidative stress, while nonasthmatics attempt to mitigate the ozone-induced response.

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Bibliografische gegevens
Hoofdauteurs: Hernandez, Michelle, Brickey, Willie June, Alexis N, Neil E., Fry, Rebecca C., Rager, Julia E., Zhou, Baiming, Ting, Jenny PY, Zhou, Haibo, Peden, David B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254026/
https://ncbi.nlm.nih.gov/pubmed/22196529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.11.007
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