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Airway cells from atopic asthmatics exposed to ozone display an enhanced innate immune gene profile

This study identifies transcriptional phenotypes of sputum samples from normal volunteers and atopic asthmatics exposed to ozone. Network analyses suggest that asthmatics elevate immune signaling following oxidative stress, while nonasthmatics attempt to mitigate the ozone-induced response.

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Detalhes bibliográficos
Main Authors: Hernandez, Michelle, Brickey, Willie June, Alexis N, Neil E., Fry, Rebecca C., Rager, Julia E., Zhou, Baiming, Ting, Jenny PY, Zhou, Haibo, Peden, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3254026/
https://ncbi.nlm.nih.gov/pubmed/22196529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.11.007
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