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TCR cross-reactivity and allorecognition: new insights into the immunogenetics of allorecognition
Alloreactive T cells are core mediators of graft rejection and are a potent barrier to transplantation tolerance. It was previously unclear how T cells educated in the recipient thymus could recognize allogeneic HLA molecules. Recently it was shown that both naïve and memory CD4(+) and CD8(+) T cell...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer-Verlag
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253994/ https://ncbi.nlm.nih.gov/pubmed/22146829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-011-0590-0 |
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