Deficits in dopamine D2 receptors and pre-synaptic dopamine in heroin dependence: commonalities and differences with other types of addiction

BACKGROUND: Positron Emission tomography (PET) imaging studies have shown that addiction to a number of substances of abuse is associated with a decrease in dopamine D(2/3) receptor binding and decreased pre-synaptic dopamine release in the striatum. Some studies have also shown that these reduction...

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Detalhes bibliográficos
Main Authors: Martinez, Diana, Saccone, Phillip A., Liu, Fei, Slifstein, Mark, Orlowska, Daria, Grassetti, Alex, Cook, Stephanie, Broft, Allegra, Van Heertum, Ronald, Comer, Sandra D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253988/
https://ncbi.nlm.nih.gov/pubmed/22015315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.08.024
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