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Chronic exposure to nicotine is associated with reduced reward-related activity in the striatum but not the midbrain

BACKGROUND: The reinforcing effects of nicotine are mediated by brain regions that also support temporal difference error (TDE) processing, yet the impact of nicotine on TDE is undetermined. METHODS: Dependent smokers (N=21) and matched controls (N=21) were trained to associate a juice reward with a...

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Autori principali: Rose, Emma Jane, Ross, Thomas J., Salmeron, Betty Jo, Lee, Mary, Shakleya, Diaa M., Huestis, Marilyn, Stein, Elliot A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253900/
https://ncbi.nlm.nih.gov/pubmed/22032832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.09.013
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