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Genetic variation in folylpolyglutamate synthase and gamma-glutamyl hydrolase and plasma homocysteine levels in the Singapore Chinese Health Study

The enzymes folylpolyglutamate synthase (FPGS) and gamma-glutamyl hydrolase (GGH) are essential for determining intracellular folate availability for one-carbon metabolism (OCM) pathways. FPGS adds glutamyl groups to the folate molecule, thereby converting folate into the preferred substrate for sev...

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Detalhes bibliográficos
Main Authors: Oppeneer, Sarah J, Ross, Julie A, Koh, Woon-Puay, Yuan, Jian-Min, Robien, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253895/
https://ncbi.nlm.nih.gov/pubmed/22018726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2011.09.035
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