H4N8 subtype avian influenza virus isolated from shorebirds contains a unique PB1 gene and causes severe respiratory disease in mice

H4N8 subtype avian influenza viruses were isolated from shorebirds in eastern Hokkaido. All the isolates shared >99.7% nucleotide homology, and all the viral genes except for PB1 were highly related to those of A/red-necked stint/Australia/1/04. Thus, the isolates were regarded as PB1 reassortant...

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Main Authors: Bui, Vuong N., Ogawa, Haruko, Xininigen, Karibe, Kazuji, Matsuo, Kengo, Awad, Sanaa S. A., Minoungou, Germaine L., Yoden, Satoshi, Haneda, Hiroaki, Ngo, Lai H., Tamaki, Shio, Yamamoto, Yu, Nakamura, Kikuyasu, Saito, Keisuke, Watanabe, Yukiko, Runstadler, Jonathan, Huettman, Falk, Happ, George M., Imai, Kunitoshi
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253874/
https://ncbi.nlm.nih.gov/pubmed/22192630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.11.019
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