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Distinction of thioredoxin transnitrosylation and denitrosylation target proteins by the ICAT quantitative approach

S-Nitrosylation is a reversible PTM for regulating protein function. Thioredoxin-1 (Trx1) catalyzes either transnitrosylation or denitrosylation of specific proteins, depending on the redox status of the cysteines within its conserved oxidoreductase CXXC motif. With a disulfide bond formed between t...

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Detalhes bibliográficos
Main Authors: Wu, Changgong, Parrott, Andrew Myles, Liu, Tong, Jain, Mohit Raja, Yang, Yanfei, Sadoshima, Junichi, Li, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253718/
https://ncbi.nlm.nih.gov/pubmed/21704743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2011.06.001
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