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Total Synthesis and Bioactivity of 18(R)-Hydroxyeicosapentaenoic Acid

[Image: see text] Resolvins are family of lipid mediators derived from omega-3 polyunsaturated fatty acids, which are generated during the resolution phase of acute inflammation. Resolvin E1 is biosynthesized from eicosapentaenoic acid via 18(R)-hydroxyeicosapentaenoic acid (18R-HEPE) in the Cox-2 a...

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Autores principales: Krishnamurthy, Venkata R., Dougherty, Ann, Haller, Carolyn A., Chaikof, Elliot L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253701/
https://ncbi.nlm.nih.gov/pubmed/21598971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo2002243
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