Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption

Glial cell line-derived neurotrophic factor (GDNF) is an essential growth factor for the survival and maintenance of the midbrain dopaminergic (DA-ergic) neurons. Activation of the GDNF pathway in the ventral tegmental area (VTA), where the GDNF receptors are expressed, produces a long-lasting suppr...

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Autori principali: Barak, S, Ahmadiantehrani, S, Kharazia, V, Ron, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253655/
https://ncbi.nlm.nih.gov/pubmed/22238721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2011.57
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