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Preparation of 2-dGuo-Treated Thymus Organ Cultures

In the thymus, immature CD4+8+ thymocytes expressing randomly rearranged T-cell receptor α- and b-chain genes undergo positive and negative selection events based on their ability to recognize self-peptide/major histocompatibility complex (MHC) molecules expressed by thymic stromal cells. In vivo an...

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Detalhes bibliográficos
Main Authors: Jenkinson, William, Jenkinson, Eric, Anderson, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253559/
https://ncbi.nlm.nih.gov/pubmed/19066498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/906
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