Conserved Herpesvirus Kinases Target the DNA Damage Response Pathway and TIP60 Histone Acetyltransferase to Promote Virus Replication

Herpesviruses, which are major human pathogens, establish life-long persistent infections. Although the α-, β-, and γ-herpesviruses infect different tissues and cause distinct diseases, they each encode a conserved serine/threonine kinase critical for virus replication and spread. The extent of subs...

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Hauptverfasser: Li, Renfeng, Zhu, Jian, Xie, Zhi, Liao, Gangling, Liu, Jianyong, Chen, Mei-Ru, Hu, Shaohui, Woodard, Crystal, Lin, Jimmy, Taverna, Sean D., Desai, Prashant, Ambinder, Richard F., Hayward, Gary S., Qian, Jiang, Zhu, Heng, Hayward, S. Diane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253558/
https://ncbi.nlm.nih.gov/pubmed/22018239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2011.08.013
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